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C is the recessive allele of the cream gene. :) The dominant version has a little r after it.

Edit: good question, because some genes are capital letters and some aren't. Cream is an incompletely dominant gene, which means that two alleles of the dominant version will act on the coat more than a single dominant allele would. :)

Okay so can someone explain why the game makers would use non-traditional ways of naming the genes? Most all scientists recognize that a capital is dominant and a lowercase is recessive. I don't mean to be rude or anything, I'm just confused. :)

Here is a scientific paper on splash white. If you scroll through and look at the pictures you can see how they label things in superscript notation.
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002653

The C gene is the albino gene series, although horses don't have an albino allele. If you look at other species with a C gene series, they have a lower case "c" for albino. See below. If horses had a recessive albino allele, it would be lower case like in cats, but "Full color" (C) is dominant.

Horses:
C = Dominant Full Color
Ccr = Incomplete Dominant Cream
Cprl = Recessive Pearl

Cats:
C = Full Color
cb = Burmese
cs = Siamese
c = Albino

Looks like the "C" gene in cats is TYR not MATP (so not relevant to each other at all)
https://www.ncbi.nlm.nih.gov/pubmed/15771720

It is worth adding that there can be many correct scientific names for the same thing. For example the actual name of the gene is SLC45A2, the protein it encodes is called Membrane-Associated Transporter Protein or MATP. SLC45A2/MATP/Cream/C etc are all fine when talking about it depending on the level of formality needed. So that alone can be confusing. And to make it worse, just because you can test for the presence of a mutation, it does not mean you know the correct name for the gene. You have to know what protein that area of DNA is encoding to know what it is comparable too in other species.

Also, and this may break horse people who have had the "no albinos" drilled into them: That whole no albino thing is nothing but breed registry politics. That is something breeders made up to get their max white/super dilute horses into registries because albino was a stigmatized term among horse people. The easiest way to prove your farm is not producing albinos is just to insist there is no such thing as an albino horse. One of the things humans get when they have MATP mutations? Oculocutaneous albinism type 4. Yes albinos can have some pigment, yes they have blue eyes. Horses have albinism by every definition EXCEPT horse people definition.